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Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections
BACKGROUND: The increasing prevalence of resistance against the last-resort antibiotic colistin is a significant threat to global public health. Here, we discovered a novel colistin resistance mechanism via enzymatic inactivation of the drug and proposed its clinical importance in microbial communit...
Autores principales: | Lee, Do-Hoon, Cha, Ju-Hee, Kim, Dae-Wi, Lee, Kihyun, Kim, Yong-Seok, Oh, Hyo-Young, Cho, You-Hee, Cha, Chang-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389796/ https://www.ncbi.nlm.nih.gov/pubmed/35982474 http://dx.doi.org/10.1186/s40168-022-01315-x |
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