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Bone marrow mesenchymal stromal cells in a 3D system produce higher concentration of extracellular vesicles (EVs) with increased complexity and enhanced neuronal growth properties

PURPOSE: Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have been demonstrated to possess great potential in preclinical models. An efficient biomanufacturing platform is necessary for scale up production for clinical therapeutic applications. The aim of this study is to...

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Detalles Bibliográficos
Autores principales: Jalilian, Elmira, Massoumi, Hamed, Bigit, Bianca, Amin, Sohil, Katz, Eitan A., Guaiquil, Victor H., Anwar, Khandaker N., Hematti, Peiman, Rosenblatt, Mark I., Djalilian, Ali R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389821/
https://www.ncbi.nlm.nih.gov/pubmed/35986305
http://dx.doi.org/10.1186/s13287-022-03128-z