Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis

Inflamed endothelial cells (ECs) trigger atherogenesis, especially at arterial regions experiencing disturbed blood flow. UCP2 (Uncoupling protein 2), a key mitochondrial antioxidant protein, improves endothelium-dependent relaxation in obese mice. However, whether UCP2 can be regulated by shear flo...

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Detalles Bibliográficos
Autores principales: Luo, Jiang-Yun, Cheng, Chak Kwong, He, Lei, Pu, Yujie, Zhang, Yang, Lin, Xiao, Xu, Aimin, Lau, Chi Wai, Tian, Xiao Yu, Ma, Ronald Ching Wan, Jo, Hanjoong, Huang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390236/
https://www.ncbi.nlm.nih.gov/pubmed/35899624
http://dx.doi.org/10.1161/CIRCRESAHA.122.321187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390236/
https://www.ncbi.nlm.nih.gov/pubmed/35899624
http://dx.doi.org/10.1161/CIRCRESAHA.122.321187

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