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Endothelial nitric oxide synthase alterations are independent of turbulence in the aorta of patients with a unicuspid aortic valve

OBJECTIVES: Certain aortic valve malformations predispose to ascending aortic aneurysm, although the mechanisms are incompletely understood. The aim of this study was to determine whether turbulence across the unicuspid aortic valve (UAV) contributes to regional differences in endothelial nitric oxi...

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Detalles Bibliográficos
Autores principales: Balint, Brittany, Kollmann, Catherine, Gauer, Simon, Federspiel, Jan M., Schäfers, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390404/
https://www.ncbi.nlm.nih.gov/pubmed/36004114
http://dx.doi.org/10.1016/j.xjon.2021.08.018