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Chronic hypoxemia induces mitochondrial respiratory complex gene expression in the fetal sheep brain

OBJECTIVE: The molecular pathways underlying hypoxemia-induced alterations in neurodevelopment of infants with congenital heart disease have not been delineated. We used transcriptome analysis to investigate differential gene expression induced by hypoxemia in an ovine artificial-womb model. METHODS...

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Detalles Bibliográficos
Autores principales: Moon, James K., Lawrence, Kendall M., Hunt, Mallory L., Davey, Marcus G., Flake, Alan W., Licht, Daniel J., Chen, Jonathan M., Kilbaugh, Todd J., Gaynor, J. William, Beiting, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390414/
https://www.ncbi.nlm.nih.gov/pubmed/36004209
http://dx.doi.org/10.1016/j.xjon.2022.04.040