Resolving the Heterogeneous Tumor-Centric Cellular Neighborhood through Multiplexed, Spatial Paracrine Interactions in the Setting of Immune Checkpoint Blockade

Direct interactions between tumor and immune cells mediate the antitumor effect of all modern cancer immunotherapeutic agents. Simultaneously, tumor cells have evolved mechanisms of evasion, including the downregulation of HLA-I, potentially disrupting the mechanism of action employed by many immune...

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Detalles Bibliográficos
Autores principales: Maus, Rachel L.G., Leontovich, Alexey A., Moore, Raymond M., Becher, Laura, Nevala, Wendy K., Flotte, Thomas J., Guo, Ruifeng, Schimke, Jill M., Dicke, Betty A., Yan, Yiyi, Markovic, Svetomir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390837/
https://www.ncbi.nlm.nih.gov/pubmed/35992329
http://dx.doi.org/10.1158/2767-9764.CRC-21-0146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390837/
https://www.ncbi.nlm.nih.gov/pubmed/35992329
http://dx.doi.org/10.1158/2767-9764.CRC-21-0146

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