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Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission

Schizophrenia is a polygenetic disease, the heterogeneity of which is likely complicated by epigenetic modifications yet to be elucidated. Here, we performed transcriptomic analysis of peripheral blood RNA from monozygotic twins discordant for schizophrenia and identified a schizophrenia-associated...

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Detalles Bibliográficos
Autores principales: Liang, Wenquan, Hou, Yu, Huang, Weiyuan, Wang, Yunqian, Jiang, Tingyun, Huang, Xingbing, Wang, Zhongju, Wu, Fengchun, Zheng, Jiawei, Zhang, Jie, Ou, Haiyan, Li, Shuyun, Ping, Junjiao, Zhang, Yuan, Ye, Junping, Li, Zhongwei, Yang, Qiong, Zhang, Jian, Zheng, Xianzhen, Li, Shufen, Zhu, Xin-Hong, Chen, Rongqing, Zhao, Cunyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390987/
https://www.ncbi.nlm.nih.gov/pubmed/35984881
http://dx.doi.org/10.1126/sciadv.abn7357