RB1 loss triggers dependence on ESRRG in retinoblastoma

Retinoblastoma (Rb) is a deadly childhood eye cancer that is classically initiated by inactivation of the RB1 tumor suppressor. Clinical management continues to rely on nonspecific chemotherapeutic agents that are associated with treatment resistance and toxicity. Here, we analyzed 103 whole exomes,...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Field, Matthew G., Kuznetsoff, Jeffim N., Zhang, Michelle G., Dollar, James J., Durante, Michael A., Sayegh, Yoseph, Decatur, Christina L., Kurtenbach, Stefan, Pelaez, Daniel, Harbour, J. William
Aineistotyyppi: Online Artikkeli Teksti
Kieli:English
Julkaistu: American Association for the Advancement of Science 2022
Aiheet:
Biomedicine and Life Sciences
Linkit:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390996/
https://www.ncbi.nlm.nih.gov/pubmed/35984874
http://dx.doi.org/10.1126/sciadv.abm8466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390996/
https://www.ncbi.nlm.nih.gov/pubmed/35984874
http://dx.doi.org/10.1126/sciadv.abm8466

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