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Nomograms of human hippocampal volume shifted by polygenic scores

Nomograms are important clinical tools applied widely in both developing and aging populations. They are generally constructed as normative models identifying cases as outliers to a distribution of healthy controls. Currently used normative models do not account for genetic heterogeneity. Hippocampa...

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Detalles Bibliográficos
Autores principales: Janahi, Mohammed, Aksman, Leon, Schott, Jonathan M, Mokrab, Younes, Altmann, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391046/
https://www.ncbi.nlm.nih.gov/pubmed/35938915
http://dx.doi.org/10.7554/eLife.78232