Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability

In this work, a UPLC-MS/MS method was developed for the determination of gypenoside A and gypenoside XLIX in rat plasma. For chromatographic separation, a UPLC BEH C18 column was employed, the mobile phase comprised acetonitrile: water (w/0.1% formic acid), and the elution time was 4 min. Detection...

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Detalles Bibliográficos
Autores principales: He, Yan, Liang, Qishun, Luo, Lvqi, He, Yifan, Huang, Xueli, Wen, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391108/
https://www.ncbi.nlm.nih.gov/pubmed/35992562
http://dx.doi.org/10.1155/2022/6734408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391108/
https://www.ncbi.nlm.nih.gov/pubmed/35992562
http://dx.doi.org/10.1155/2022/6734408

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