Downregulation of Inflammatory Response via Nrf2/Trx1/TXNIP Axis in Oxidative Stress-Induced ARPE-19 Cells and Mouse Model of AMD

AIM: Chronic inflammation is crucial for age-related macular degeneration (AMD) pathogenesis. However, the mechanism involved in activating inflammation remains unclear. This study is aimed at investigating whether nuclear factor erythrocyte-associated factor 2 (Nrf2) negatively regulated the Nod-li...

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Detalles Bibliográficos
Autores principales: Yang, Qian, Cai, Wenting, Jin, Huizi, Shen, Tianyi, Yu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391142/
https://www.ncbi.nlm.nih.gov/pubmed/35993020
http://dx.doi.org/10.1155/2022/1497813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391142/
https://www.ncbi.nlm.nih.gov/pubmed/35993020
http://dx.doi.org/10.1155/2022/1497813

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