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Downregulation of Inflammatory Response via Nrf2/Trx1/TXNIP Axis in Oxidative Stress-Induced ARPE-19 Cells and Mouse Model of AMD

AIM: Chronic inflammation is crucial for age-related macular degeneration (AMD) pathogenesis. However, the mechanism involved in activating inflammation remains unclear. This study is aimed at investigating whether nuclear factor erythrocyte-associated factor 2 (Nrf2) negatively regulated the Nod-li...

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Detalles Bibliográficos
Autores principales:	Yang, Qian, Cai, Wenting, Jin, Huizi, Shen, Tianyi, Yu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391142/ https://www.ncbi.nlm.nih.gov/pubmed/35993020 http://dx.doi.org/10.1155/2022/1497813

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