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A High-Throughput Fluorescent Turn-On Assay for Inhibitors of DHHC Family Proteins
[Image: see text] As the “writer” enzymes of protein S-acylation, a dynamic and functionally significant post-translational modification (PTM), DHHC family proteins have emerged in the past decade as both key modulators of cellular homeostasis and as drivers of neoplastic, autoimmune, metabolic, and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391280/ https://www.ncbi.nlm.nih.gov/pubmed/35816339 http://dx.doi.org/10.1021/acschembio.2c00193 |