Cargando…

A High-Throughput Fluorescent Turn-On Assay for Inhibitors of DHHC Family Proteins

[Image: see text] As the “writer” enzymes of protein S-acylation, a dynamic and functionally significant post-translational modification (PTM), DHHC family proteins have emerged in the past decade as both key modulators of cellular homeostasis and as drivers of neoplastic, autoimmune, metabolic, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Tian, Azizi, Saara-Anne, Brookes, Noah, Lan, Tong, Dickinson, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391280/
https://www.ncbi.nlm.nih.gov/pubmed/35816339
http://dx.doi.org/10.1021/acschembio.2c00193

Ejemplares similares