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Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition

Incomplete repair after acute kidney injury can lead to development of chronic kidney disease. To define the mechanism of this response, we compared mice subjected to identical unilateral ischemia-reperfusion kidney injury with either contralateral nephrectomy (where tubule repair predominates) or c...

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Detalles Bibliográficos
Autores principales: Xu, Leyuan, Guo, Jiankan, Moledina, Dennis G., Cantley, Lloyd G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391331/
https://www.ncbi.nlm.nih.gov/pubmed/35986026
http://dx.doi.org/10.1038/s41467-022-32634-0