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Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons

How animals rewire cellular programs to survive cold is a fascinating problem with potential biomedical implications, ranging from emergency medicine to space travel. Studying a hibernation-like response in the free-living nematode Caenorhabditis elegans, we uncovered a regulatory axis that enhances...

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Detalles Bibliográficos
Autores principales: Pekec, Tina, Lewandowski, Jarosław, Komur, Alicja A., Sobańska, Daria, Guo, Yanwu, Świtońska-Kurkowska, Karolina, Małecki, Jędrzej M., Dubey, Abhishek Anil, Pokrzywa, Wojciech, Frankowski, Marcin, Figiel, Maciej, Ciosk, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391379/
https://www.ncbi.nlm.nih.gov/pubmed/35986016
http://dx.doi.org/10.1038/s41467-022-32500-z