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Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons
How animals rewire cellular programs to survive cold is a fascinating problem with potential biomedical implications, ranging from emergency medicine to space travel. Studying a hibernation-like response in the free-living nematode Caenorhabditis elegans, we uncovered a regulatory axis that enhances...
Autores principales: | Pekec, Tina, Lewandowski, Jarosław, Komur, Alicja A., Sobańska, Daria, Guo, Yanwu, Świtońska-Kurkowska, Karolina, Małecki, Jędrzej M., Dubey, Abhishek Anil, Pokrzywa, Wojciech, Frankowski, Marcin, Figiel, Maciej, Ciosk, Rafal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391379/ https://www.ncbi.nlm.nih.gov/pubmed/35986016 http://dx.doi.org/10.1038/s41467-022-32500-z |
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