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Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation
To generate sufficient numbers of transplantable hematopoietic stem cells (HSCs) in vitro, a detailed understanding of how this process takes place in vivo is essential. The endothelial-to-hematopoietic transition (EHT), which culminates in the production of the first HSCs, is a highly complex proce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391417/ https://www.ncbi.nlm.nih.gov/pubmed/35905741 http://dx.doi.org/10.1016/j.stemcr.2022.06.008 |