Cargando…

Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation

To generate sufficient numbers of transplantable hematopoietic stem cells (HSCs) in vitro, a detailed understanding of how this process takes place in vivo is essential. The endothelial-to-hematopoietic transition (EHT), which culminates in the production of the first HSCs, is a highly complex proce...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaidan, Nada, Nitsche, Leslie, Diamanti, Evangelia, Hannah, Rebecca, Fidanza, Antonella, Wilson, Nicola K., Forrester, Lesley M., Göttgens, Berthold, Ottersbach, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391417/
https://www.ncbi.nlm.nih.gov/pubmed/35905741
http://dx.doi.org/10.1016/j.stemcr.2022.06.008