METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner

Uncontrolled epithelial cell proliferation in the prostate transition zone and the hyper-accumulation of mesenchymal-like cells derived from the epithelial-mesenchymal transition (EMT) of prostatic epithelium are two key processes in benign prostatic hyperplasia (BPH). m(6)A RNA modification affects...

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Detalles Bibliográficos
Autores principales: Li, Jiaren, Yao, Hanyu, Huang, Jin, Li, Chao, Zhang, Yichuan, Xu, Ran, Wang, Zhenting, Long, Zhi, Tang, Jin, Wang, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391461/
https://www.ncbi.nlm.nih.gov/pubmed/35985997
http://dx.doi.org/10.1038/s41419-022-05162-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391461/
https://www.ncbi.nlm.nih.gov/pubmed/35985997
http://dx.doi.org/10.1038/s41419-022-05162-4

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