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Integrin β1, PDGFRβ, and type II collagen are essential for meniscus regeneration by synovial mesenchymal stem cells in rats

Synovial mesenchymal stem cells (MSCs) injected into the knee promote meniscus regeneration in several animal models; however, the mode of action is unknown. Our purpose was to identify the molecules responsible for this meniscus regeneration. Rat synovial MSCs were treated with neutralizing antibod...

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Detalles Bibliográficos
Autores principales: Kitahashi, Tsukasa, Kogawa, Ryo, Nakamura, Kentaro, Sekiya, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391488/
https://www.ncbi.nlm.nih.gov/pubmed/35986079
http://dx.doi.org/10.1038/s41598-022-18476-2