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Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

Regenerative therapies aimed at replacing photoreceptors are a promising approach for the treatment of otherwise incurable causes of blindness. However, such therapies still face significant hurdles, including the need to improve subretinal delivery and long-term survival rate of transplanted cells,...

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Detalles Bibliográficos
Autores principales: Ripolles-Garcia, Ana, Dolgova, Natalia, Phillips, M. Joseph, Savina, Svetlana, Ludwig, Allison L., Stuedemann, Sara A., Nlebedum, Uchenna, Wolfe, John H., Garden, Oliver A., Maminishkis, Arvydas, Amaral, Juan, Bharti, Kapil, Gamm, David M., Aguirre, Gustavo D., Beltran, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391525/
https://www.ncbi.nlm.nih.gov/pubmed/35905738
http://dx.doi.org/10.1016/j.stemcr.2022.06.009