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Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs
Regenerative therapies aimed at replacing photoreceptors are a promising approach for the treatment of otherwise incurable causes of blindness. However, such therapies still face significant hurdles, including the need to improve subretinal delivery and long-term survival rate of transplanted cells,...
Autores principales: | Ripolles-Garcia, Ana, Dolgova, Natalia, Phillips, M. Joseph, Savina, Svetlana, Ludwig, Allison L., Stuedemann, Sara A., Nlebedum, Uchenna, Wolfe, John H., Garden, Oliver A., Maminishkis, Arvydas, Amaral, Juan, Bharti, Kapil, Gamm, David M., Aguirre, Gustavo D., Beltran, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391525/ https://www.ncbi.nlm.nih.gov/pubmed/35905738 http://dx.doi.org/10.1016/j.stemcr.2022.06.009 |
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