Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression

Krüppel-like factor 4 (KLF4) is a transcription factor that has been proven necessary for both induction and maintenance of pluripotency and self-renewal. Whole-genome sequencing defined a unique mutation in KLF4 (KLF4(K409Q)) in human meningiomas. However, the molecular mechanism of this tumor-spec...

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Detalles Bibliográficos
Autores principales: Tsytsykova, Alla V., Wiley, Graham, Li, Chuang, Pelikan, Richard C., Garman, Lori, Acquah, Francis A., Mooers, Blaine H.M., Tsitsikov, Erdyni N., Dunn, Ian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391581/
https://www.ncbi.nlm.nih.gov/pubmed/35996584
http://dx.doi.org/10.1016/j.isci.2022.104839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391581/
https://www.ncbi.nlm.nih.gov/pubmed/35996584
http://dx.doi.org/10.1016/j.isci.2022.104839

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