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Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression
Krüppel-like factor 4 (KLF4) is a transcription factor that has been proven necessary for both induction and maintenance of pluripotency and self-renewal. Whole-genome sequencing defined a unique mutation in KLF4 (KLF4(K409Q)) in human meningiomas. However, the molecular mechanism of this tumor-spec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391581/ https://www.ncbi.nlm.nih.gov/pubmed/35996584 http://dx.doi.org/10.1016/j.isci.2022.104839 |