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Spatially resolved transcriptomic profiling of ovarian aging in mice

Ovarian aging precedes that of any other mammalian organ and is the primary cause of female age-related infertility. The biological mechanisms responsible for ovarian aging remain unclear. Previous studies have been limited by their use of bulk RNA-sequencing, which masks the dynamic and heterogeneo...

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Detalles Bibliográficos
Autores principales: Russ, Jennifer E., Haywood, Mary E., Lane, Sydney L., Schoolcraft, William B., Katz-Jaffe, Mandy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391589/
https://www.ncbi.nlm.nih.gov/pubmed/35996587
http://dx.doi.org/10.1016/j.isci.2022.104819