In silico Drug Repurposing of Anticancer Drug 5-FU and Analogues Against SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics Simulation, Pharmacokinetics and Chemical Reactivity Studies

BACKGROUND: Since the last COVID-19 outbreak, several approaches have been given a try to quickly tackle this global calamity. One of the well-established strategies is the drug repurposing, which consists in finding new therapeutic uses for approved drugs. Following the same paradigm, we report in...

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Detalles Bibliográficos
Autores principales: Matondo, Aristote, Dendera, Washington, Isamura, Bienfait Kabuyaya, Ngbolua, Koto-te-Nyiwa, Mambo, Hilaire V S, Muzomwe, Mayaliwa, Mudogo, Virima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391940/
https://www.ncbi.nlm.nih.gov/pubmed/35996620
http://dx.doi.org/10.2147/AABC.S366111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391940/
https://www.ncbi.nlm.nih.gov/pubmed/35996620
http://dx.doi.org/10.2147/AABC.S366111

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