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In silico Drug Repurposing of Anticancer Drug 5-FU and Analogues Against SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics Simulation, Pharmacokinetics and Chemical Reactivity Studies

BACKGROUND: Since the last COVID-19 outbreak, several approaches have been given a try to quickly tackle this global calamity. One of the well-established strategies is the drug repurposing, which consists in finding new therapeutic uses for approved drugs. Following the same paradigm, we report in...

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Detalles Bibliográficos
Autores principales:	Matondo, Aristote, Dendera, Washington, Isamura, Bienfait Kabuyaya, Ngbolua, Koto-te-Nyiwa, Mambo, Hilaire V S, Muzomwe, Mayaliwa, Mudogo, Virima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391940/ https://www.ncbi.nlm.nih.gov/pubmed/35996620 http://dx.doi.org/10.2147/AABC.S366111

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