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HER2 drives lung fibrosis by activating a metastatic cancer signature in invasive lung fibroblasts

Progressive tissue fibrosis, including idiopathic pulmonary fibrosis (IPF), is characterized by excessive recruitment of fibroblasts to sites of tissue injury and unremitting extracellular matrix deposition associated with severe morbidity and mortality. However, the molecular mechanisms that contro...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Geng, Yan, Liang, Jiurong, Coelho, Ana Lucia, Yao, Changfu, Deng, Nan, Wang, Yizhou, Dai, Kristy, Huang, Guanling, Xie, Ting, Liu, Ningshan, Rowan, Simon C., Taghavifar, Forough, Kulur, Vrishika, Liu, Zhenqiu, Stripp, Barry R., Hogaboam, Cory M., Jiang, Dianhua, Noble, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391950/
https://www.ncbi.nlm.nih.gov/pubmed/35980387
http://dx.doi.org/10.1084/jem.20220126