Cargando…
HER2 drives lung fibrosis by activating a metastatic cancer signature in invasive lung fibroblasts
Progressive tissue fibrosis, including idiopathic pulmonary fibrosis (IPF), is characterized by excessive recruitment of fibroblasts to sites of tissue injury and unremitting extracellular matrix deposition associated with severe morbidity and mortality. However, the molecular mechanisms that contro...
Autores principales: | Liu, Xue, Geng, Yan, Liang, Jiurong, Coelho, Ana Lucia, Yao, Changfu, Deng, Nan, Wang, Yizhou, Dai, Kristy, Huang, Guanling, Xie, Ting, Liu, Ningshan, Rowan, Simon C., Taghavifar, Forough, Kulur, Vrishika, Liu, Zhenqiu, Stripp, Barry R., Hogaboam, Cory M., Jiang, Dianhua, Noble, Paul W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9391950/ https://www.ncbi.nlm.nih.gov/pubmed/35980387 http://dx.doi.org/10.1084/jem.20220126 |
Ejemplares similares
-
Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis
por: Xie, Ting, et al.
Publicado: (2021) -
Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis
por: Xie, Ting, et al.
Publicado: (2018) -
Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis
por: Liang, Jiurong, et al.
Publicado: (2023) -
The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis
por: Liang, Jiurong, et al.
Publicado: (2022) -
Categorization of lung mesenchymal cells in development and fibrosis
por: Liu, Xue, et al.
Publicado: (2021)