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The influence of HLA/HIV genetics on the occurrence of elite controllers and a need for therapeutics geotargeting view

The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count, even without antiretrovirals. There is a lot of diversity in HIV subtypes and HLA alleles. The most common sub...

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Detalles Bibliográficos
Autores principales: Lunardi, Luciano Werle, Bragatte, Marcelo Alves de Souza, Vieira, Gustavo Fioravanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392165/
https://www.ncbi.nlm.nih.gov/pubmed/34562387
http://dx.doi.org/10.1016/j.bjid.2021.101619