AMPK/SIRT1 Deficiency Drives Adjuvant-Induced Arthritis in Rats by Promoting Glycolysis-Mediated Monocytes Inflammatory Polarization

BACKGROUND: Exact roles of many metabolic regulators in rheumatoid arthritis (RA) are to be clarified. This study aimed to further characterize the impacts of silent information regulator 1 (SIRT1) status changes on this disease. METHODS: Fluctuation pattern of SIRT1 expression in adjuvant-induced a...

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Detalles Bibliográficos
Autores principales: Wang, Dan-Dan, He, Chi-Yi, Wu, Yi-Jin, Xu, Liang, Shi, Chao, Olatunji, Opeyemi Joshua, Zuo, Jian, Ji, Cong-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392262/
https://www.ncbi.nlm.nih.gov/pubmed/35996683
http://dx.doi.org/10.2147/JIR.S378090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392262/
https://www.ncbi.nlm.nih.gov/pubmed/35996683
http://dx.doi.org/10.2147/JIR.S378090

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