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PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome

BACKGROUND: Cohesin is an important structural regulator of the genome, regulating both three-dimensional genome organization and gene expression. The core cohesin trimer interacts with various HEAT repeat accessory subunits, yielding cohesin complexes of distinct compositions and potentially distin...

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Detalles Bibliográficos
Autores principales: Arruda, Nicole L., Bryan, Audra F., Dowen, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392266/
https://www.ncbi.nlm.nih.gov/pubmed/35986423
http://dx.doi.org/10.1186/s13072-022-00463-6