Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m(6)A-mediated degradation of STEAP3 mRNA

BACKGROUND: Hypoxia, a typical hallmark of solid tumors, exhibits an essential role in the progression of colorectal cancer (CRC), in which the dysregulation of long non-coding RNAs (lncRNAs) is frequently observed. However, the underlying mechanisms are not clearly defined. METHODS: The TCGA databa...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Jiang, Jingwen, Huang, Zhao, Jin, Ping, Peng, Liyuan, Luo, Maochao, Zhang, Zhe, Chen, Yan, Xie, Na, Gao, Wei, Nice, Edouard C., Li, Jing-Quan, Chen, Hai-Ning, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392287/
https://www.ncbi.nlm.nih.gov/pubmed/35986274
http://dx.doi.org/10.1186/s12943-022-01638-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392287/
https://www.ncbi.nlm.nih.gov/pubmed/35986274
http://dx.doi.org/10.1186/s12943-022-01638-1

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