YAP1-MAML2 fusion in a pediatric NF2-wildtype intraparenchymal brainstem schwannoma

Biallelic inactivation of NF2 represents the primary or sole oncogenic driver event in the vast majority of schwannomas. We report on a four-year-old female who underwent subtotal resection of a right medullary intraparenchymal schwannoma. RNA sequencing revealed an in-frame fusion between exon 5 of...

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Detalles Bibliográficos
Autores principales: Karajannis, Matthias A., Li, Bryan K., Souweidane, Mark M., Liechty, Benjamin, Yao, JinJuan, Benhamida, Jamal K., Bale, Tejus A., Rosenblum, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392329/
https://www.ncbi.nlm.nih.gov/pubmed/35986430
http://dx.doi.org/10.1186/s40478-022-01423-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392329/
https://www.ncbi.nlm.nih.gov/pubmed/35986430
http://dx.doi.org/10.1186/s40478-022-01423-7

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