Effects of toxic apolipoprotein E fragments on Tau phosphorylation and cognitive impairment in neonatal mice under sevoflurane anesthesia

BACKGROUND: Anesthesia induces Tau phosphorylation and cognitive impairment in young, but not adult, mice. Apolipoprotein E (ApoE) may play a protective role in neuronal activity and injury repair, whereas its toxic fragments are reported to induce neurodegeneration and neurocognitive impairment in...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Yang, Man, Zhuang, Xiaoli, Pan, Jiacheng, Zhao, Yue, Yu, Yonghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392520/
https://www.ncbi.nlm.nih.gov/pubmed/35810473
http://dx.doi.org/10.1002/brb3.2702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392520/
https://www.ncbi.nlm.nih.gov/pubmed/35810473
http://dx.doi.org/10.1002/brb3.2702

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