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The protective mechanism of protein kinase R to inhibit neuronal ferroptosis in cerebral injury from subarachnoid hemorrhage

Purpose: To investigate the role and mechanism of protein kinase R (PKR) in subarachnoid hemorrhage (SAH)‐mediated ferroptosis. Methods: A rat SAH model was constructed and treated with PKR inhibitor C16 to observe SAH and neurological impairment in rats and to detect malonaldehyde (MDA), iron ions...

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Detalles Bibliográficos
Autores principales: Lei, Jianwei, Song, Shuxin, Chen, Zhihua, Shu, Sihong, Liu, Qiang, Hu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392539/
https://www.ncbi.nlm.nih.gov/pubmed/35894766
http://dx.doi.org/10.1002/brb3.2722