Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats

OBJECTIVE(S): Diabetes mellitus (DM) affects the pharmacokinetics of drugs. Ranolazine is an antianginal drug that is prescribed in DM patients with angina. We decided to evaluate the effect of DM on the pharmacokinetics of ranolazine and its major metabolite CVT-2738 in rats. MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Mashayekhi-sardoo, Habibeh, Kamali, Hossein, Mehri, Soghra, Sahebkar, Amirhossein, Imenshahidi, Mohsen, Mohammadpour, Amir Hooshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392571/
https://www.ncbi.nlm.nih.gov/pubmed/36033953
http://dx.doi.org/10.22038/IJBMS.2022.64391.14156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392571/
https://www.ncbi.nlm.nih.gov/pubmed/36033953
http://dx.doi.org/10.22038/IJBMS.2022.64391.14156

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