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Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats
OBJECTIVE(S): Diabetes mellitus (DM) affects the pharmacokinetics of drugs. Ranolazine is an antianginal drug that is prescribed in DM patients with angina. We decided to evaluate the effect of DM on the pharmacokinetics of ranolazine and its major metabolite CVT-2738 in rats. MATERIALS AND METHODS:...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392571/ https://www.ncbi.nlm.nih.gov/pubmed/36033953 http://dx.doi.org/10.22038/IJBMS.2022.64391.14156 |