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Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells

OBJECTIVE(S): STATs are one of the initial targets of emerging anti-cancer agents due to their regulatory roles in survival, apoptosis, drug response, and cellular metabolism in CML. Aberrant STAT3 activity promotes malignancy, and acts as a metabolic switcher in cancer cell metabolism, contributing...

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Detalles Bibliográficos
Autores principales: Tezcanli Kaymaz, Burcin, Selvi Gunel, Nur, Sogutlu, Fatma, Ozates Ay, Neslihan Pinar, Baran, Yusuf, Gunduz, Cumhur, Biray Avci, Cigir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392574/
https://www.ncbi.nlm.nih.gov/pubmed/36033954
http://dx.doi.org/10.22038/IJBMS.2022.64138.14121