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A tissue-level phenome-wide network map of colocalized genes and phenotypes in the UK Biobank

Phenome-wide association studies identified numerous loci associated with traits and diseases. To help interpret these associations, we constructed a phenome-wide network map of colocalized genes and phenotypes. We generated colocalized signals using the Genotype-Tissue Expression data and genome-wi...

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Detalles Bibliográficos
Autores principales: Rocheleau, Ghislain, Forrest, Iain S., Duffy, Áine, Bafna, Shantanu, Dobbyn, Amanda, Verbanck, Marie, Won, Hong-Hee, Jordan, Daniel M., Do, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392744/
https://www.ncbi.nlm.nih.gov/pubmed/35987940
http://dx.doi.org/10.1038/s42003-022-03820-z