Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor in the SYSCOL cohort, we find that expression of the hominid-restrict...

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Detalles Bibliográficos
Autores principales: Simó-Riudalbas, Laia, Offner, Sandra, Planet, Evarist, Duc, Julien, Abrami, Laurence, Dind, Sagane, Coudray, Alexandre, Coto-Llerena, Mairene, Ercan, Caner, Piscuoglio, Salvatore, Andersen, Claus Lindbjerg, Bramsen, Jesper Bertram, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392749/
https://www.ncbi.nlm.nih.gov/pubmed/35987910
http://dx.doi.org/10.1038/s41467-022-32649-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392749/
https://www.ncbi.nlm.nih.gov/pubmed/35987910
http://dx.doi.org/10.1038/s41467-022-32649-7

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