Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading

In Alzheimer’s disease (AD), younger symptom onset is associated with accelerated disease progression and tau spreading, yet the mechanisms underlying faster disease manifestation are unknown. To address this, we combined resting-state fMRI and longitudinal tau-PET in two independent samples of cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Frontzkowski, Lukas, Ewers, Michael, Brendel, Matthias, Biel, Davina, Ossenkoppele, Rik, Hager, Paul, Steward, Anna, Dewenter, Anna, Römer, Sebastian, Rubinski, Anna, Buerger, Katharina, Janowitz, Daniel, Binette, Alexa Pichet, Smith, Ruben, Strandberg, Olof, Carlgren, Niklas Mattsson, Dichgans, Martin, Hansson, Oskar, Franzmeier, Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392750/
https://www.ncbi.nlm.nih.gov/pubmed/35987901
http://dx.doi.org/10.1038/s41467-022-32592-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392750/
https://www.ncbi.nlm.nih.gov/pubmed/35987901
http://dx.doi.org/10.1038/s41467-022-32592-7

Ejemplares similares