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A cutback in Imiquimod cutaneous toxicity; comparative cutaneous toxicity analysis of Imiquimod nanotransethosomal gel with 5% marketed cream on the BALB/c mice

Herein, Imiquimod (IMQ) was incorporated in nanotransethosomes (nTES) to develop the IMQ-nTES nano-drug delivery system. IMQ-nTES was optimized using 2(3) factorial design. The optimized formulation was expressed with a particle size of 192.4 ± 1.60 nm, Poly-dispersibility of 0.115 ± 0.008, and IMQ...

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Detalles Bibliográficos
Autores principales: Jamshaid, Humzah, Din, Fakhar ud, Malik, Maimoona, Mukhtiar, Muhammad, Choi, Han Gon, Ur-Rehman, Tofeeq, Khan, Gul Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392762/
https://www.ncbi.nlm.nih.gov/pubmed/35987944
http://dx.doi.org/10.1038/s41598-022-18671-1