Pan-cancer analysis of mRNA stability for decoding tumour post-transcriptional programs

Measuring mRNA decay in tumours is a prohibitive challenge, limiting our ability to map the post-transcriptional programs of cancer. Here, using a statistical framework to decouple transcriptional and post-transcriptional effects in RNA-seq data, we uncover the mRNA stability changes that accompany...

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Detalles Bibliográficos
Autores principales: Perron, Gabrielle, Jandaghi, Pouria, Moslemi, Elham, Nishimura, Tamiko, Rajaee, Maryam, Alkallas, Rached, Lu, Tianyuan, Riazalhosseini, Yasser, Najafabadi, Hamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392771/
https://www.ncbi.nlm.nih.gov/pubmed/35987939
http://dx.doi.org/10.1038/s42003-022-03796-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392771/
https://www.ncbi.nlm.nih.gov/pubmed/35987939
http://dx.doi.org/10.1038/s42003-022-03796-w

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