Direct observation of heterogeneous formation of amyloid spherulites in real-time by super-resolution microscopy

Protein misfolding in the form of fibrils or spherulites is involved in a spectrum of pathological abnormalities. Our current understanding of protein aggregation mechanisms has primarily relied on the use of spectrometric methods to determine the average growth rates and diffraction-limited microsc...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Pinholt, Henrik D., Zhou, Xin, Bohr, Søren S.-R., Banetta, Luca, Zaccone, Alessio, Foderà, Vito, Hatzakis, Nikos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392779/
https://www.ncbi.nlm.nih.gov/pubmed/35987792
http://dx.doi.org/10.1038/s42003-022-03810-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392779/
https://www.ncbi.nlm.nih.gov/pubmed/35987792
http://dx.doi.org/10.1038/s42003-022-03810-1

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