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Direct observation of heterogeneous formation of amyloid spherulites in real-time by super-resolution microscopy
Protein misfolding in the form of fibrils or spherulites is involved in a spectrum of pathological abnormalities. Our current understanding of protein aggregation mechanisms has primarily relied on the use of spectrometric methods to determine the average growth rates and diffraction-limited microsc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392779/ https://www.ncbi.nlm.nih.gov/pubmed/35987792 http://dx.doi.org/10.1038/s42003-022-03810-1 |