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Feasibility and application of machine learning enabled fast screening of poly-beta-amino-esters for cartilage therapies

Despite the large prevalence of diseases affecting cartilage (e.g. knee osteoarthritis affecting 16% of population globally), no curative treatments are available because of the limited capacity of drugs to localise in such tissue caused by low vascularisation and electrostatic repulsion. While an e...

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Detalles Bibliográficos
Autores principales: Perni, Stefano, Prokopovich, Polina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392801/
https://www.ncbi.nlm.nih.gov/pubmed/35987777
http://dx.doi.org/10.1038/s41598-022-18332-3