Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells

BACKGROUND: Eosinophilic inflammation is a hallmark of refractory chronic rhinosinusitis (CRS) and considered a major therapeutic target. Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL‐1β overproduction, thereby suggesting autophagy regulation...

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Detalles Bibliográficos
Autores principales: Lee, Jinju, Kim, So Jeong, Choi, Go Eun, Yi, Eunbi, Park, Hyo Jin, Choi, Woo Seon, Jang, Yong Ju, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393075/
https://www.ncbi.nlm.nih.gov/pubmed/35988262
http://dx.doi.org/10.1002/ctm2.1021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393075/
https://www.ncbi.nlm.nih.gov/pubmed/35988262
http://dx.doi.org/10.1002/ctm2.1021

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