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A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells
The self-renewal and pluripotency of embryonic stem cells (ESCs) are conferred by networks including transcription factors and histone modifiers. The Auxin-inducible degron (AID) system can rapidly and reversibly degrade its target proteins and is becoming a powerful tool to explore novel function o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393215/ https://www.ncbi.nlm.nih.gov/pubmed/36003152 http://dx.doi.org/10.3389/fcell.2022.964119 |