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A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells

The self-renewal and pluripotency of embryonic stem cells (ESCs) are conferred by networks including transcription factors and histone modifiers. The Auxin-inducible degron (AID) system can rapidly and reversibly degrade its target proteins and is becoming a powerful tool to explore novel function o...

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Detalles Bibliográficos
Autores principales: Li, Jingsheng, Dai, Chunhong, Xie, Wenyan, Zhang, Heyao, Huang, Xin, Chronis, Constantinos, Ye, Ying, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393215/
https://www.ncbi.nlm.nih.gov/pubmed/36003152
http://dx.doi.org/10.3389/fcell.2022.964119