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Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity

Streptococcus pneumoniae is an encapsulated gram-negative bacterium and a significant human pathogen. The capsular polysaccharide (CPS) is essential for virulence and a target antigen for vaccines. Although widespread introduction of pneumococcal conjugate vaccines (PCVs) has significantly reduced d...

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Detalles Bibliográficos
Autores principales: Richardson, Nicole I., Kuttel, Michelle M., Ravenscroft, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393222/
https://www.ncbi.nlm.nih.gov/pubmed/36003080
http://dx.doi.org/10.3389/fmolb.2022.961532